The Role of Dll4/Notch Signaling in Normal and Pathological Ocular Angiogenesis: Dll4 Controls Blood Vessel Sprouting and Vessel Remodeling in Normal and Pathological Conditions

Figure 5

Pathological neovascularization in OIR (oxygen-induced retinopathy model) at P16 and Dll4 expression in OIR at P16. Dll4 is expressed in the capillaries, arteries (a), and pathological neovascular tufts (yellow arrows) in OIR in pathological angiogenesis but at a lower level in veins (V). X-gal staining: 4x (a, c) and 10x (b, d, e) magnification. Yellow arrows indicate pathological neovascular tufts.

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