Assessment of Global and Local Alterations in Retinal Layer Thickness in Ins2 (Akita) Diabetic Mice by Spectral Domain Optical Coherence Tomography

Table 2

Inner retinal thickness (IRT), outer retinal thickness (ORT), total retinal thickness (TRT), and photoreceptor outer segment length (OSL) in Akita and wild-type mice at 12 and 24 weeks of age.

Variable (microns)	Age (weeks)	Akita	Wild-type	% difference	value
					Condition	Age	Condition  age
IRT	12	92 ± 3	94 ± 4	−2.13	0.02	0.4	0.8
	24	92 ± 4	96 ± 6	−4.17
ORT	12	112 ± 5	114 ± 3	−1.75	0.008	0.3	0.4
	24	112 ± 2	115 ± 2	−2.61
TRT	12	203 ± 8	208 ± 6	−2.40	0.004	0.3	0.6
	24	204 ± 5	211 ± 7	−3.32
OSL	12	26 ± 2	26 ± 2	0.00	0.3	0.1	1.0
	24	27 ± 2	26 ± 2	+3.85