Review Article

Complications Associated with the Use of Expandable Gases in Vitrectomy

Table 1

The incidence of raised intraocular pressure after vitrectomy with gas tamponade.

AuthorIncidence of IOP elevation (%)Definition of IOP elevationType of surgical interventionGasRisk factors for IOP elevation

Abrams et al. [28]45≥30 mmHg in the early postoperative periodPPV with SF6 to reform soft eyesSF6 20–100%Eyes with postoperative fibrinous anterior chamber exudates, 100% gas concentration
Chang et al. [26]58.9>22 mmHg within the first postoperative weekPPV for complicated retinal detachmentC2F6–C3F8 in various concentrationsN/A
The Silicone Study Group [29]8.7≥30 mmHg at any postoperative visitPPV in eyes with proliferative vitreoretinopathy and prior vitrectomyC3F8 14%N/A
The Silicone Study Group [30]6.1≥30 mmHg at any postoperative visitPPV in eyes with proliferative vitreoretinopathy and prior vitrectomySF6 20%N/A
Wong et al. [31]21.7>30 mmHg on postoperative Day-1PPV with or without phacoemulsification cataract surgeryC3F8 16%N/A
Wong et al. [31]20.4>30 mmHg on postoperative Day-1PPV with or without phacoemulsification cataract surgerySF6 30%N/A
Chen and Thompson [32]43>25 mmHg in early postoperative periodPPV with or without scleral bucklingSF6 10–30% or C3F8 5%–35%Increasing patient age; expansile gas concentrations; use of C3F8; circumferential scleral buckles
Chen [33]52>30 mmHg within 1 week after surgeryPPV for macular hole surgeryC3F8 14%N/A
Mittra et al. [34]52.4 (>25 mmHg) 28.6 (>30 mmHg)Elevation 4–6 hours postoperativelyPPVSF6 18%–20% or C3F8 12%–16%N/A
Wong et al. [5]0.5–1.3N/AVitreoretinal surgeryN/AN/A

Abbreviations: IOP, intraocular pressure; PPV, pars plana vitrectomy. The study by Wong et al. [5] presenting the incidence of IOP elevation in all vitreoretinal procedures is presented for comparative purposes.