Comparison of SNP Genotypes Related to Proliferative Vitreoretinopathy (PVR) across Slovenian and European Subpopulations
Table 1
Simulation of genotype distribution in a potential population dataset.
Number of simulations
Genotype case dataset (n)
Number of genotypes added to the case dataset (n)
Allele frequency
MAF
value
AA
AG
GG
AA
AG
GG
A
G
1
1
39
73
0
0
0
0.18
0.82
0.18
0.130
2
1
40
73
0
1
0
0.18
0.82
0.18
0.110
3
1
41
73
0
2
0
0.19
0.81
0.19
0.092
4
1
42
73
0
3
0
0.19
0.81
0.19
0.078
5
1
43
73
0
4
0
0.19
0.81
0.19
0.066
6
1
44
73
0
5
0
0.19
0.81
0.19
0.056
7
1
45
73
0
6
0
0.20
0.80
0.20
0.047
8
2
39
73
1
0
0
0.19
0.81
0.19
0.091
9
2
40
73
1
1
0
0.19
0.81
0.19
0.077
10
2
41
73
1
2
0
0.19
0.81
0.19
0.065
11
2
42
73
1
3
0
0.20
0.80
0.20
0.055
12
2
43
73
1
4
0
0.20
0.80
0.20
0.047
13
3
39
73
2
0
0
0.20
0.80
0.20
0.065
14
3
40
73
2
1
0
0.20
0.80
0.20
0.055
15
3
41
73
2
2
0
0.20
0.80
0.20
0.046
16
4
39
73
3
0
0
0.20
0.80
0.20
0.041
Note: original case dataset is shown in the second column. The control dataset is not shown. Added genotypes to the original dataset are represented in the third column. Genotypes were added one by one in each homozygote or heterozygote category. Allele frequency, MAF, and values changed according to the performed simulation.
