Journal of Ophthalmology

Research Article

DNA Methylation Status of the Interspersed Repetitive Sequences for LINE-1, Alu, HERV-E, and HERV-K in Trabeculectomy Specimens from Glaucoma Eyes

Table 2

LINE-1 methylation levels in glaucoma eyes and control eyes.
% mC% mCmC% mCuC% uCmC% uCuC
Normal control1050.8810 ± 3.435618.2732 ± 2.525723.2248 ± 2.128024.1912 ± 0.480034.3107 ± 3.6554
POAG1649.8650 ± 3.013617.4822 ± 2.509923.7864 ± 1.828023.5895 ± 0.857635.1419 ± 2.5862
PACG1249.8900 ± 1.800917.9876 ± 2.238222.2586 ± 2.900223.5921 ± 0.461636.1617 ± 0.7060
Secondary glaucoma1449.3133 ± 1.537117.2674 ± 1.877623.0947 ± 2.402523.5456 ± 0.389336.0923 ± 0.6032
All values are presented as mean ± standard deviation. % mC = percentage of LINE-1 methylation; % mCmC = percentage of LINE-1 hypermethylated loci number; % mCuC, % uCmC = percentage of LINE-1 partially methylated loci; % uCuC = percentage of LINE-1 hypomethylated loci number.