Evaluation of Vitrectomy with Planned Foveal Detachment as Surgical Treatment for Refractory Diabetic Macular Edema with or without Vitreomacular Interface Abnormality

Table 1

Pre- and postoperative characteristics of groups 1 and 2.

Variable studied	Group 1	Group 2	value
Number of eyes in each group	21	7
Age mean ± SD (years)	53.38 ± 8.2	52.7 ± 3.4
OCT findings
Presence of neurosensory detachment preoperatively	9 (42.9%)	4 (57.1%)	0.51
Presence of VMA preoperatively	3 (14.3%)	3 (42.9%)	0.11
Intact ellipsoid zone	10 (47.6%)	3 (42.9%)	0.827
Preop. continuous ELM	9 (42.9%)	3 (42.9%)	1.0
Postop. continuous ELM	13 (69.9%)	3 (42.9%)	0.3
Preoperative CMT mean ± SD (μm)	521.3 ± 83.6	420.2 ± 56.3
Postoperative CMT (final visit) mean ± SD (μm)	282.3 ± 20.8	249.4 ± 45.7	0.019
Preoperative injection history
Bevacizumab + aflibercept	10 (47.6%)	3 (42.9%)	0.11
Ranibizumab + aflibercept	12 (57.1%)	4 (57.1%)	1.0
CST after anti-VEGF failure	8 (38.1%)	4 (57.1%)
BCVA (decimal form)
Preoperative	0.16 ± 0.07	0.34 ± 0.09
Postoperative (final visit)	0.37 ± 0.14	0.7 ± 0.16	0.185
Recurrence of edema within FU period	6 (28.6%)	0 (0.0%)	0.1
Follow-up period in months	10.57 ± 1.1	10.86 ± 1.2

Mann–Whitney test.