Pulse Waveform Analysis of the Ocular Blood Flow Using Laser Speckle Flowgraphy before and after Glaucoma Treatment
Table 1
Demographic and ocular characteristics of patients with glaucoma treated with prostaglandin analogs or trabeculectomy.
PG analogs group
Trabeculectomy group
N = 28
N = 23
Demographic characteristics
Sex (male/female)
10/18
10/13
Age (years)
50.6 ± 10.8
60.0 ± 9.7
Ocular characteristics
POAG/NTG
4/24
19/4
Refraction (diopter)
−4.3 ± 3.2
−4.3 ± 2.9
MD (dB)
−4.8 ± 5.0
−14.3 ± 7.4
PSD (dB)
7.6 ± 4.0
11.8 ± 4.1
CCT (μm)
520.9 ± 30.5
520.8 ± 28.2
Pretreatment IOP (mmHg)
16.0 ± 2.8
19.1 ± 3.8
Pretreatment MOPP (mmHg)
43.0 ± 12.5
43.0 ± 11.7
Pretreatment heart rate (beats/min)
70.9 ± 12.6
66.7 ± 11.9
Pretreatment MBP (mmHg)
85.6 ± 13.2
93.2 ± 15.7
Intraocular pressure decrease rate (%)
26.0 ± 5.0
42.2 ± 14.3
Clinical characteristics
Hypertension
4
6
Pretreatment glaucoma medications
0
23
Prostaglandin analogs
0
23 (100%)
Beta-blockers
0
20 (87.0%)
Carbonic anhydrase
0
22 (95.7%)
Rho kinase inhibitors
0
9 (39.1%)
Alpha-2-sympathomimetic drugs
0
18 (78.3%)
The data are presented as means ± standard deviations. POAG: primary open-angle glaucoma; NTG: normal-tension glaucoma; MD: mean deviation; PSD: pattern standard deviation; CCT: central cornea thickness; IOP: intraocular pressure; MOPP: mean ocular perfusion pressure; MBP: mean blood pressure; PG: prostaglandin analogs.