Relationship between Neovascular Density in Swept Source-Optical Coherence Tomography Angiography and Signs of Activity in Exudative Age-Related Macular Degeneration
Clinically active hypodense choroidal neovascularization. (a) Numerous well-defined vessels (arrows) without capillaries, small branches, or terminal loops were depicted by Topcon’s DRI Triton swept source-optical coherence tomography angiography (SS-OCTA) in a 4.5 × 4.5 mm en-face cube corresponding to (b) an outer retina B-scan segmentation image. (c) The same lesion was highlighted by an extensive nonvascularized halo in (d) a 4.5 × 4.5 mm choriocapillaris B-scan. (e) No neovascular vessels nor evidence of clinical activity was visible on infrared fundus photography of the same macular region. (f) Intraretinal fluid (arrows) and hyperreflective dots (arrow-heads) as well as an irregular retinal pigment epithelium detachment were observed in the spectral domain-OCT B-scan (Cirrus HD 4000, Zeiss).
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.