Clinical Study

Corneal Safety and Stability in Cases of Small Incision Lenticule Extraction with Collagen Cross-Linking (SMILE Xtra)

Table 2

Visual acuity and refraction along the postoperative follow-up period.

1 month3 months6 months12 months24 months

SMILE Xtra: UDVA (logMAR)0.068 ± 0.080.033 ± 0.070.031 ± 0.060.030 ± 0.060.031 ± 0.06
SMILE: UDVA (logMAR)0.041 ± 0.070.031 ± 0.060.029 ± 0.060.028 ± 0.060.028 ± 0.05
value0.0030.1240.1220.1300.144
SMILE Xtra: CDVA (logMAR)0.021 ± 0.09−0.028 ± 0.07−0.042 ± 0.06−0.051 ± 0.05−0.055 ± 0.05
SMILE: CDVA (logMAR)0.002 ± 0.07−0.038 ± 0.06−0.048 ± 0.06−0.055 ± 0.06−0.057 ± 0.05
value<0.0010.0310.1710.1900.272
SMILE Xtra: MRSE (D)−0.12 ± 0.23−0.16 ± 0.25−0.19 ± 0.21−0.20 ± 0.21−0.18 ± 0.19
SMILE: MRSE (D)−0.18 ± 0.19−0.20 ± 0.22−0.21 ± 0.21−0.22 ± 0.20−0.19 ± 0.18
value<0.0010.0380.2670.2780.361

Values are expressed as mean ± SD. SD: standard deviation; UDVA: uncorrected distance visual acuity; CDVA: corrected distance visual acuity; value compares mean of SMILE Xtra vs. SMILE using independent-samples t-test. Statistically significant.