HGF-rs12536657 and Ocular Biometric Parameters in Hyperopic Children, Emmetropic Adolescents, and Young Adults: A Multicenter Quantitative Trait Study

Table 2

Logistic regression gender-adjusted results for different genotypes of HGF SNP rs12536657 under an additive genetic model of hyperopic children compared with all emmetropic patients (a); hyperopic children compared with emmetropic children (b); and hyperopic children with emmetropic adults (c).

SNP rs5712536657	Genotype	Hyperopic children ()	Emmetropic children and adults ()	OR	95% CI for OR
(a)							0.206
	GG	116 (62.70)	135 (63.08)	1.00
	GA	63 (34.05)	65 (30.37)	1.18	0.76	1.82	0.458
	AA	6 (3.24)	14 (6.54)	0.47	0.17	1.27	0.136
SNP rs12536657	Genotype	Hyperopic children ()	Emmetropic children ()	OR	95% CI for OR
(b)							0.30
	GG	116 (62.7%)	34 (65.4%)	1.00
	GA	63 (34.1%)	14 (26.9%)	0.76	0.38	1.52	0.439
	AA	6 (3.2%)	4 (7.7%)	2.26	0.607	8.47	0.228
SNP rs12536657	Genotype	Hyperopic children ()	Emmetropic adults ()	OR	95% CI for OR
(c)							0.23
	GG	116 (62.7%)	101 (62.3%)	1.00
	GA	63 (34.1%)	51 (31.5%)	1.16	0.73	1.86	0.531
	AA	6 (3.2%)	10 (6.2%)	0.45	0.15	1.30	0.140

Missing genotype data: in the hyperopic group, 3 genotypes were missing (). Missing genotype data: 1 genotype was missing in the emmetropic adult group ( and ).