Increased Plasma Levels of 8-Hydroxy-2′-deoxyguanosine (8-OHdG) in Patients with Pseudoexfoliation Glaucoma

Table 1

Demographic characteristics and 8-hydroxydeoxyguanosine (8-OHdG) levels between pseudoexfoliation glaucoma cases and controls.

Variables	Cases ()	Controls ()	value
Age in years, mean (SD)	62.27 (6.31)	59.91 (8.33)	0.146^a
Male/female, n	26/15	30/15	0.751^b
Systemic diseases, n (%)
Diabetes mellitus	6 (14.6)	6 (13.3)	0.862^b
Hypertension	4 (9.7)	5 (11.1)	0.605^b
Coronary artery disease	2 (4.8)	2 (4.4)	0.924^b
Hypercholesterolemia	3 (7.3)	2 (4.4)	0.569^b
Family history of glaucoma	5 (12.2)	1 (2.2)	0.069^b
Smokers	5 (12.2)	5 (11.1)	0.874^b
8-OHdG concentration, ng/mL
Mean (SD)	30.48 (31.52)	16.95 (10.66)	0.008^a
Median	18.11	13.78	0.032^c
By gender
Males, mean (SD)	29.53 (26.94)	17.02 (11.02)	0.023^a
Median	18.17	13.12	0.041^c
Females, mean (SD)	32.12 (39.22)	16.80 (10.29)	0.154^a
Median	17.68	17.97	0.442^c

Notes. ^aIndependent sample t-test (two-tailed); ^bchi-square test; ^cMann–Whitney U test.