Early Alterations of Corneal Subbasal Plexus in Uncomplicated Type 1 Diabetes Patients
Table 3
Correlation r () of corneal parameters in the T1DM group with clinical and metabolic data.
Corneal nerves parameters
Age
Age at onset
Duration of DM
BMI (kg/m2)
HBA1c (%)
Nerve fiber length (µm/frame)
0.01
1.535 (0.018)
−0.657 (0.002)
−0.6 (0.007)
0.068
Nerve fiber length density (µm/mm2)
−0.021
1.524 (0.021)
−0.666 (0.002)
−0.6 (0.007)
0.074
Number of fibers (no./mm2)
−0.060
1.444 (0.05)
−0.610 (0.006)
−0.587 (0.008)
−0.062
Number of branchings (no.)
−0.013
0.237
−0.305
−0.293
−0.210
Number of beadings (no.)
−0.228
0.088
−0.355
0.044
0.406
Beadings density (no./mm)
−0.210
−0.124
−0.075
0.404
0.292
Nerve fiber tortuosity
0.344
0.258
0.056
−0.202
−0.188
No significant correlations were found between the corneal parameters and HbA1c. BMI of the T1DM group was highly related to the nerve fiber length (r = −0.6, ), the nerve fiber length density (r = −0.6, ), and the number of fibers (r = −0.587, ) (Table 4).
