Review Article

Inverted Internal Limiting Membrane Flap Technique versus Internal Limiting Membrane Peeling for Vitrectomy in Highly Myopic Eyes with Macular Hole-Induced Retinal Detachment: An Updated Meta-Analysis

Table 1

The baseline patient characteristics of the included studies.

StudyCountryStudy typeNumber of participants (eyes)Mean age (years)Gender (female/male)Axial length (mm)Outcome measuresFollow-up

Baba et al. [19]JapanRetrospective observational studyILM flap: 1074 (55–89)5/528.95(27.03–31.00)MH closure, retinal reattachment, BCVA9.4 (6.0–27.5)
ILM Peeling:1168 (55–88)8/330.30(27.80–32.28)19.4 (6.0–48.4)
Sasaki et al. [20]JapanRetrospective studyILM flap: 675.0 ± 6.45/130.47 ± 2.57MH closure, retinal reattachment, BCVA6
ILM peeling: 966.0 ± 12.57/230.10 ± 1.956
Chen and Yang [26]TaiwanRetrospective interventional studyILM flap: 2062.06 ± 8.904/1628.40 ± 1.94MH closure, BCVA8.92 ± 3.23
ILM peeling: 2060.53 ± 8.786/1429.35 ± 1.8814.13 ± 6.66
Hu et al. [27]ChinaRetrospective studyILM flap: 1958.8 ± 13.816/329.4 ± 1.9MH closure, BCVA17.6 ± 11.3
ILM peeling: 2159.9 ± 8.515/630.0 ± 2.423.4 ± 16.1
Matsumura et al. [28]JapanRetrospective interventional studyILM flap: 1067.7 ± 9.78/228.4 ± 2.2MH closure, retinal reattachment, BCVA12
ILM peeling: 1275.3 ± 8.711/130.4 ± 1.612
Takahashi et al. [29]JapanRetrospective studyILM flap: 1668.4 ± 7.814/229.1 ± 1.9MH closure, retinal reattachment, BCVA12
ILM peeling: 1669.1 ± 8.515/129.6 ± 1.112
Wakabayashi et al. [30]JapanRetrospective studyILM flap: 1367.8 ± 9.911/229.4 ± 0.9MH closure, retinal reattachment, BCVA12
ILM peeling: 3669.2 ± 9.134/229.6 ± 1.712