Identification of Key Genes and Pathways Associated with Age-Related Macular Degeneration

Figure 1

Ingenuity pathway analysis of the total significantly differentially expressed genes to identify the canonical pathways involved in RPE/choroid of AMD. The top ten significant pathways identified for the DEGs (blue bar). The orange curve shows the ratio between the number of DEGs and the total number of genes in each of these pathways (see the entire list of IPA pathways in Supplementary Table S5 online).