Alterations in Parafoveal and Optic Disc Vessel Densities in Patients with Obstructive Sleep Apnea Syndrome

Table 3

Comparison of the age- and sex-corrected macular thickness (ETDRS) values of OSAS groups with healthy controls using generalized estimating equation models.

Macula thickness outer ring (6 mm) and inner ring (3 mm)	Control (n = 27, 54 eyes)	Mild OSAS (n = 27, 54 eyes)	Moderate OSAS (n = 24, 48 eyes)	Severe OSAS (n = 26, 52 eyes)
Outer ring superior	329.81 ± 19.86	326.30 ± 17.66; −3.507, −12.823/5.809; 0.461	323.84 ± 23.87; −5.969, −17.091/5.154; 0.293	319.38 ± 15.94; −10.432, −19.632/−1.232; 0.026
Outer ring nasal	341.68 ± 20.91	333.96 ± 18.21; −7.724, −17.543/2.095; 0.123	331.61 ± 14.83; −8.204, −19.219/2.810; 0.144	330.48 ± 12.30; −8.504, −19.314/−0.823; 0.033
Outer ring inferior	330.94 ± 20.81	322.11 ± 25.12; −8.820, −20.302/2.643; 0.131	317.87 ± 22.57; −13.072, 23.989/2.158; 0.019	316.09 ± 19.49; −12.848, −24.555/-1.142; 0.031
Outer ring temporal	323.74 ± 20.70	317.76 ± 21.28; −5.972, −16.404/4.464; 0.262	308.70 ± 19.70; −8.625, −19.516/2.265; 0.121	305.11 ± 15.09; −15.039, −25.358/−4.720; 0.004
Inner ring superior	347.24 ± 21.75	342.69 ± 16.33; −4.548, −14.394/5.297; 0.365	340.63 ± 12.34; −6.602, −15.527/2.322; 0.147	336.53 ± 12.76; −10.702, −22.111/0.706; 0.066
Inner ring nasal	345.27 ± 20.84	334.48 ± 48.04; −10.797, 26.693/5.099; 0.183	338.80 ± 14.70; −6.469, −15.267/2.328; 0.150	336.15 ± 20.99; −9.124, −19.982/1.734; 0.100
Inner ring inferior	343.31 ± 22.81	338.40 ± 20.32; −4.911, −15.826/2.328; 0.378	333.91 ± 19.68; −9.400, −19.878/1.078; 0.079	331.86 ± 23.84; −11.449, −23.209/0.310; 0.056
Inner ring temporal	330.40 ± 19.50	327.94 ± 18.01; −2.465, −11.947/7.017; 0.610	325.78 ± 14.50; −4.620, −13.052/3.812; 0.283	322.34 ± 20.08; −8.061, −18.075/1.953; 0.115

Macula map regions within a 6 × 6 mm area centered on the fovea, as defined by the ETDRS. values of comparisons between the control group are represented within parentheses.