Research Article

Clinical Presentations and Outcomes of Retinoblastoma Patients in relation to the Advent of New Multimodal Treatments: A 12-Year Report from Single Tertiary Referral Institute in Thailand

Table 2

Treatment modalities and globe salvage rates for intraocular tumor according to International Classification of Retinoblastoma (ICRB).

Treatment modalities, n = 115ICRB group, eyes (globe salvage, %)
ABCDE
UnilateralBilateralUnilateralBilateralUnilateralBilateralUnilateralBilateralUnilateralBilateral

CRD4 (100%)1 (100%)9 (100%)2 (100%)9 (66.7%)2 (0%)19 (47.4%)
CRD + plaque2 (100%)1 (100%)
CRD + EBRT1 (100%)1 (0%)
CRD + IAC2 (100%)1 (100%)4 (75%)4 (100%)3 (0%)6 (33.3%)
CRD + IAC + IVT1 (100%)2 (100%)1 (100%)
CRD + IAC + plaque4 (75%)1 (0%)
CRD + IVT + plaque2 (50%)
CRD + IAC + IVT + plaque1 (100%)1 (0%)
IAC1 (0%)1 (100%)3 (67.7%)1 (0%)
IAC + IVT1 (100%)
IAC + IVT + plaque1 (0%)
Primary enucleation (in our center/from referral hospital)2 (1/1)1 (0/1)7 (7/0)13 (8/5)
Secondary enucleation (in our center/from referral hospital)15 (5/0)5 (5/0)6 (6/0)15 (14/1)

Total04 (100%)1 (100%)18 (94.4%)1 (100%)5 (100%)14 (50%)17 (64.7%)16 (18.8%)39 (28.2%)

ICRB = International Classification of Retinoblastoma; CRD = chemoreduction; IAC = intra-arterial chemotherapy; EBRT = external beam radiation therapy; IVT = intravitreal chemotherapy.