Safety and Efficacy of Bleb Needling with Antimetabolite after Trabeculectomy Failure in Glaucoma Patients: A Systemic Review and Meta-Analysis

Table 2

Estimates with 95% confidence interval for complication rates after bleb needling.

	Overall		5-Fu		MMC
	Estimate (%)	95% CI	Estimate (%)	95% CI	Estimate (%)	95% CI
Conjunctival haemorrhage	5.7	[2.5%, 10.1%]	2.7	[1.1%, 4.9%]	10.8	[2.9%, 22.9%]
Hyphema	5.5	[3.0%, 8.7%]	3.9	[1.8%, 6.8%]	7.4	[3.0%, 13.6%]
Bleb leakage	5.0	[3.2%, 7.3%]	5.3	[2.9%, 8.4%]	4.8	[2.1%, 8.4%]
Hypotony	4.3	[2.9%, 6.0%]	3.6	[1.9%, 5.9%]	6.0	[3.0%, 8.0%]
Shallow anterior chamber	3.4	[1.6%, 5.8%]	1.7	[0.6%, 3.4%]	5.6	[1.9%, 11.0%]
Serous choroidal detachment	2.6	[1.2%, 4.5%]	1.5	[0.6%, 2.7%]	4.1	[1.3%, 8.5%]
Corneal punctuate epitheliopathy	2.4	[1.1%, 4.2%]	2.0	[0.4%, 4.7%]	2.9	[1.1%, 5.6%]
Choroidal effusion	1.3	[0.6%, 2.1%]	1.5	[0.7%, 2.7%]	1.0	[0.2%, 2.3%]

CI: confidence interval; MMC: mitomycin C; 5-Fu: 5-fluorouracil.