Clinical Study

Comparisons of Ocular Anatomic Differences of Lens-Subluxated Eye with or without Acute Angle Closure: A Retrospective Study

Table 3

Comparison of ocular parameters of the participants included in this study.

ParametersAAC group (n = 30)Non-AAC group (n = 30)-value-value
Affected eyesFellow eyes-valueAffected eyesFellow eyes-value

Ultrasound biomicroscopy
 ACD (mm)1.82 ± 0.602.58 ± 0.690.00013.63 ± 0.943.91 ± 0.910.0780.00010.0001
 1AOD500 (mm)0.06 ± 0.030.25 ± 0.110.00010.50 ± 0.080.49 ± 0.110.5250.00010.0001
 LV (mm)1.60 ± 0.110.68 ± 0.250.00010.38 ± 0.110.40 ± 0.100.6230.00010.0001
 I-curve (mm)0.19 ± 0.060.19 ± 0.080.8450.17 ± 0.060.19 ± 0.040.1510.1210.814
 IT750 (mm)0.38 ± 0.040.37 ± 0.070.4230.37 ± 0.050.36 ± 0.050.3900.5130.391
 Zonular compromise (laxity or loss) (n)3000.00013000.00011.0001.000
  1 quadrant (n)2400.00012200.00010.5491.000
  2 quadrants (n)6080
  ≥3 quadrants (n)0000
Gonioscopy
 Modified Shaffer grade, 0–41.57 ± 0.623.13 ± 0.580.00013.80 ± 0.413.59 ± 0.510.1200.00010.0001
IOL master
 AL (mm)23.66 ± 0.8823.93 ± 1.300.33425.88 ± 2.6125.93 ± 2.750.9370.00010.001
Other clinical data
 Lens nucleus opacity, LOCS III2.16 ± 0.362.13 ± 0.290.6932.25 ± 0.472.17 ± 0.330.4290.4410.680
 Lens thickness4.31 ± 0.274.31 ± 0.250.9884.32 ± 0.274.31 ± 0.240.9140.8640.928
 C/D ratio0.31 ± 0.080.29 ± 0.080.3480.28 ± 0.050.29 ± 0.040.6970.3400.069
 RNFL thickness (μm)97.75 ± 9.3399.59 ± 8.850.26097.37 ± 7.4898.18 ± 9.910.8400.5710.242

Data shown are presented as mean ± SD, analyzed with the Mann–Whitney U test and Student’s t-test. : affected eyes versus fellow eyes. : AAC group versus the non-AAC group in affected eyes; : AAC group versus the non-AAC group in fellow eyes. Respectively, anterior segment parameters and zonular evaluation were measured by ultrasound biomicroscopy. Axial length was measured by IOL Master. Grading of anterior chamber angle was evaluated by gonioscopy. Lens nucleus opacity and C/D ratio were observed in slit lamp. RNFL thickness was measured by optical coherence tomography. ACD, anterior chamber depth; AOD 500, angle opening distance at 500 μm from scleral spur; LV, lens vault; I-curve, iris curvature; IT 750, iris thickness at 750 μm from scleral spur; AL, axial length; LOCS III, Lens Opacities Classification System III; C/D ratio, cup/disk ratio; RNFL, retinal nerve fiber layer; AAC, acute angle closure; n, number.