Research Article
The Anterior Chamber Injection of Moxifloxacin Injection to Prevent Endophthalmitis after Cataract Surgery: A Meta-analysis
Table 1
Characteristics of the included studies (n = 8).
| Study | Site | Designs | The number of the eyes | Age | Treatment options | Follow-up | Outcomes | Moxifloxacin | Control | Moxifloxacin | Control |
| Melega et al. [11] | Brazil | RCT | 1818 | 1822 | 68.50 ± 9.72 | 68.49 ± 9.63 | 0.5% moxifloxacin | 6 w | ECD, IOP, CCT, and the incidence of endophthalmitis | Lane et al. [17] | USA | RCT | 26 | 31 | 74 ± 9.3 | 74 ± 9.3 | 0.5% moxifloxacin | 3 m | UCVA, IOP, ECD, and CCT | Cetinkaya et al. [12] | Turkey | Case-control study | 33 | 32 | 64.81 ± 11.61 | 65.43 ± 11.10 | 0.5% moxifloxacin | 1 y | BCVA, IOP, and corneal edema | Rudnisky et al. [13] | Canada | Case-control study | 33039 | 42256 | NA | NA | 0.5% moxifloxacin | 6 w | The incidence of endophthalmitis | Virgilio et al. [18] | Colombia | Cohort study | 1618 | 1056 | 67.2 ± 11.3 | 67.2 ± 11.3 | 0.5% moxifloxacin | 2 w | The incidence of endophthalmitis | Matsuura et al. [15] | Japan | Cohort study | 69 | 69 | 71.9 ± 7.5 | 71.9 ± 7.5 | 0.5% moxifloxacin | 3 m | UCVA, BCVA, IOP, ECD, and CCT | Matsuura et al., [16] | Japan | Cohort study | 18797 | 15958 | NA | NA | 0.1%, 0.3%, and 0.5% moxifloxacin | 1 m | The incidence of endophthalmitis | Vieira et al. [14] | Brazil | Cohort study | 3680 | 3515 | 67.7 ± 9.03 | 68.1 ± 8.92 | 0.5% moxifloxacin | 1 m | The incidence of endophthalmitis |
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Abbreviations: BCVA, best corrected visual acuity; UCVA, uncorrected visual acuity; IOP, intraocular pressure; ECD, corneal endothelial cell density; CCT, central corneal thickness; NA, data not available; y, year; m, month; w, week.
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