Research Article

Relationship between Serum Vascular Endothelial Growth Factor Levels and Stages of Diabetic Retinopathy and Other Biomarkers

Table 1

Demographics and clinical characteristics of DM type 2 patients included in the study. The table shows the comparison of means for each demographic and clinical finding for patients not affected (no DR) and affected by DR (NPDR and PDR).

ParameterAll DM type 2 participantsDR group
N or (mean ± SD)No DR groupDR groupNPDR groupPDR group

Males/females29/3364/4127/1437/27
Age (mean in years)61 ± 11.160 ± 10.263 ± 10.958 ± 9.6
BMI (kg/m2)29 ± 6.330 ± 5.330 ± 5.130 ± 5.6
HbA1c (%)7.2 ± 1.68.1 ± 2.08.1 ± 1.88.1 ± 1.6
TC (mg/dL)165 ± 45.8178 ± 71.4165 ± 54.4186 ± 79.2
TGs (mg/dL)178 ± 118.5181 ± 112.2167 ± 108.8190 ± 112
HDL (mg/dL)44 ± 13.440 ± 38.839 ± 20.540 ± 47.2
LDL (mg/dL)101 ± 37.1106 ± 49.096 ± 40.3112 ± 52.8
Irisin (ng/mL)174 ± 27.799 ± 27.5114 ± 22.490 ± 25.6

values <0.05. DR: diabetic retinopathy. NPDR: nonproliferative diabetic retinopathy. PDR: proliferative diabetic retinopathy. BMI: body mass index. HbA1c: glycosylated hemoglobin. TC: total cholesterol. TGs: triglycerides. HDL: high-density lipoprotein. LDL: low-density lipoprotein.