Research Article

Short-Term Results of Switch from Conbercept to Bevacizumab or Ranibizumab in Eyes with Persistent Neovascular Age-Related Macular Degeneration

Table 2

The proportions of improved response stratified by CNV type at 1 month after switching.

Type 1 CNVType 2 CNVPCVMixed CNV value

CMTn = 21n = 5n = 25n = 13
 Improved, n (%)9 (42.9%)3 (60.0%)16 (64.0%)8 (61.5%)0.439
 Unimproved, n (%)12 (57.1%)2 (40.0%)9 (36.0%)5 (38.5%)

mPEDHn = 18n = 4n = 24n = 13
 Improved, n (%)13 (72.2%)3 (75.0%)17 (70.8%)7 (53.8%)0.780
 Unimproved, n (%)5 (27.8%)1 (25.0%)7 (29.2%)6 (46.2%)

cPEDHn = 10n = 3n = 19n = 7
 Improved, n (%)6 (60.0%)1 (33.3%)11 (57.9%)3 (42.9%)0.751
 Unimproved, n (%)4 (40.0%)2 (66.7%)8 (42.1%)4 (57.1%)

IRFn = 21n = 5n = 25n = 13
 Improved, n (%)1 (4.8%)1 (20%)5 (20%)1 (7.7%)0.245
 Unimproved, n (%)20 (95.2%)4 (80%)20 (80%)12 (92.3%)

SRFn = 21n = 5n = 25n = 13
 Improved, n (%)3 (14.3%)0 (0%)4 (16%)1 (7.7%)0.701
 Unimproved, n (%)18 (85.7%)5 (100%)21 (84%)12 (92.3%)

BCVAn = 21n = 5n = 25n = 13
 Improved, n (%)9 (42.9%)0 (0%)12 (48%)6 (46.2%)0.604
 Unimproved, n (%)12 (57.1%)5 (100%)13 (52%)7 (53.8%)

CMT, central macular thickness; mPEDH, maximum PED height; cPEDH, PED height at foveal center; PED, pigmented epithelial detachment; IRF, intraretinal fluid; SRF, subretinal fluid; BCVA, best-corrected visual acuity; CNV, choroidal neovascularization; PCV, polypoidal choroidal vasculopathy.