Research Article

Symptoms of Dry Eye Disease in Hospitalized Patients with Coronavirus Disease 2019 (COVID-19)

Table 2

The laboratory findings of COVID-19 patients with DED symptoms.

Laboratory examinationMedian (SD)
OSDI scoreDEQ-5 score
NO DED (score ≤12) (n = 14, 33.33%)DED (score≥13) (n = 28, 66.67%) valueNO DED (score≤5) (n = 16, 38.10%)DED (score≥6) (n = 26, 61.9%) value

Blood routine (count, 109/L)
 Hemoglobin118.50 (17.64)112.86 (18.37)0.35120.19 (15.78)111.39 (18.92)0.13
 White blood cell5.43 (1.60)5.61 (1.67)0.745.79 (1.21)5.40 (1.85)0.45
 Neutrophil3.49 (1.28)3.20 (1.07)0.443.66 (1.01)3.07 (1.17)0.11
 Lymphocyte1.44 (0.48)1.62 (0.50)0.281.49 (0.42)1.60 (0.54)0.50
 Monocytes0.45 (0.19)0.52 (0.18)0.250.46 (0.13)0.52 (0.21)0.34
 Platelet253.36 (140.27)254.57 (81.92)0.97222.56 (80.09)273.62 (112.24)0.12
Biochemical tests
 ALT (IU/L)49.50 (55.48)27.21 (16.93)0.0641.81 (31.01)30.23 (38.28)0.31
 AST (IU/L)42.14 (48.45)20.86 (14.26)0.0433.31 (42.12)24.65 (22.71)0.39
 Serum creatinine (μmmol/L)67.86 (40.23)61.06 (15.06)0.4370.43 (36.85)58.96 (15.40)0.17
 Serum urea nitrogen (mmol/L)4.57 (2.27)4.59 (1.47)0.984.29 (2.22)4.76 (1.40)0.40
 Creatine kinase (IU/L)45.54 (21.37)48.43 (30.77)0.7642.800 (17.60)50.23 (32.41)0.42
 D-Dimer (mg/L)1.15 (1.56)0.87 (1.24)0.521.32 (2.00)0.74 (0.65)0.18
 PCT (ng/L)0.06 (0.08)0.05 (0.08)0.770.05 (0.04)0.06 (0.09)0.70
Serum cytokines
 TNF-α452.09 (608.27)400.46 (163.80)0.71420.33 (594.99)416.14 (139.40)0.98
 IL-2 receptor7.01 (4.21)6.59 (1.26)0.677.17 (4.05)6.48 (1.18)0.47