Research Article

Logistic Regression Model Using Scheimpflug-Placido Cornea Topographer Parameters to Diagnose Keratoconus

Table 2

The mean values of shape indices and aberrations in keratoconus and normal groups.

ParameterKeratoconus mean ± SD (range)Normal mean ± SD (range) value

Shape indices
Anterior rf (D)46.83 ± 6.24 (30.63, 81.45)42.59 ± 1.36 (39.63, 46.20)0.01>
Anterior rs (D)51.15 ± 8.60 (40.86, 113.3)43.95 ± 1.53 (41.03, 48.91)0.01>
Anterior Q0.01 ± 1.17 (−5.45, 3.14)0.84 ± 0.36 (−0.22, 1.47)0.01>
Anterior RMS/A (μm/mm2)0.20 ± 0.14 (0.01, 1.17)0.02 ± 0.02 (0.01, 0.24)0.01>
Posterior rf (D)−7.17 ± 1.46 (−12.76, −3.34)−5.93 ± 0.22 (−6.38, −4.73)0.01>
Posterior rs (D)−7.69 ± 5.32 (−15.85, 48.20)−6.06 ± 1.95 (−6.87, 11)0.01>
Posterior (p)−0.36 ± 1.60 (−3.47, 7.19)0.80 ± 0.55 (−0.58, 4.33)0.01>
Posterior RMS/A (μm/mm2)0.63 ± 0.63 (0.06, 5.69)0.10 ± 0.06 (0.03, 0.70)0.01>

Aberrations
Total
OPD (µm)2.94 ± 2.43 (0.32, 14.44)0.95 ± 0.85 (0.25, 6.29)0.01>
HOAs (µm)1.57 ± 1.35 (0.19, 10.18)0.37 ± 0.42 (0.15, 4.64)0.01>
Astigmatism Z (2, ±2) (µm)2.37 ± 2.15 (0.02, 13.37)0.83 ± 0.78 (0.02, 4.25)0.01>
Coma Z (3, ±1) (µm)1.10 ± 0.80 (0.08, 5.51)0.17 ± 0.17 (0.01, 1.82)0.01>
Spheric Z (4, 0) (µm)0.26 ± 0.34 (0.01, 2.97)0.16 ± 0.18 (0.02, 1.74)0.042
Residual HOAs (µm)0.89 ± 0.95 (0.13, 6.50)0.27 ± 0.38 (0.06, 4.03)0.01>

Anterior
OPD (µm)2.84 ± 1.68 (0.37, 9.97)0.96 ± 0.72 (0.20, 3.73)0.01>
HOAs (µm)1.62 ± 1.09 (0.23, 8.59)0.27 ± 0.11 (0.14, 1.05)0.01>
Astigmatism Z (2, ±2) (µm)2.21 ± 1.49 (0.05, 9.38)0.89 ± 0.74 (0.01, 3.71)0.01>
Coma Z (3, ±1) (µm)1.36 ± 0.97 (0.10, 6.44)0.15 ± 0.09 (0.02, 0.69)0.01>
Spheric Z (4, 0) (µm)0.30 ± 0.36 (0.01, 2.87)0.13 ± 0.04 (0.03, 0.28)0.01>
Residual HOAs (µm)0.72 ± 0.63 (0.09, 4.96)0.16 ± 0.10 (0.06, 0.79)0.01>

Posterior
OPD (µm)0.94 ± 0.82 (0.12, 5.71)0.27 ± 0.40 (0.09, 4.42)0.01>
HOAs (µm)0.75 ± 0.69 (0.08, 5.32)0.21 ± 0.39 (0.05, 4.12)0.01>
Astigmatism Z (2, ±2) (µm)0.49 ± 0.46 (0.01, 2.60)0.15 ± 0.14 (0.04, 1.59)0.01>
Coma Z (3, ±1) (µ)0.35 ± 0.33 (0.02, 1.88)0.04 ± 0.11 (0, 1.31)0.01>
Spheric Z (4, 0) (µm)0.12 ± 0.14 (0, 1.27)0.03 ± 0.15 (0, 1.72)0.01>
Residual HOAs (µm)0.74 ± 1.53 (0.06, 16)0.20 ± 0.35 (0.04, 3.64)0.01>

Mann–Whitney U test. SD: standard deviation; rf = apical radius of the flattest meridian of the aspherotoric surface in 4.5 mm zone of the cornea; rs = apical radius of the steepest meridian of the aspherotoric surface in 4.5 mm zone of the cornea; Q = mean asphericity in 4.5 mm zone of the cornea; RMS/A: root mean square values per unit area in 4.5 mm zone of the cornea, OPD = total wavefront error; HOAs = higher-order aberrations.