The Role of Intravitreal Anti-VEGF Agents in Rabbit Eye Model of Open-Globe Injury

Table 1

Intravitreal proliferation stage classified via proliferative responses and corresponding B scan manifestations.

Intravitreal proliferation stage	Proliferative responses^†	B scan manifestations^†
Stage 0	No proliferative response	Normal
Stage 1	Vitreous haze, vitreous strands	Vitreous opacity, without membranous echo connected to the retina
Stage 2	Epiretinal membrane formation with retinal folds	Membranous echo connected to the retina, without local retinal detachment
Stage 3	White dense membrane covering the retina with localized retinal detachments and retinal folds	Surface of the retina not smooth; significant vitreous traction and retinal detachment

^†Proliferative responses and corresponding B scan manifestations were summarized according to previous studies.