Alterations in Mucin-Associated Gene Expression on the Ocular Surface in Active and Stable Stages of Atopic and Vernal Keratoconjunctivitis

Table 3

Characteristics of three cluster groups of allergic conjunctival disease patients.

	Cluster 1	Cluster 2	Cluster 3	value
Clinical score (points) (median (range))	114 (103–223)	13 (2–23)	7.5 (3–12)	0.000003
SPDEF (relative expression level) (median (range))	1.9 (1.24–4.97)	7.3 (0.74–14.9)	34.6 (2.93–64.5)	0.002
MUC16 (relative expression level) (median (range))	0.36 (0.09–0.96)	0.33 (0.26–0.45)	1.19 (1.11–2.00)	0.00008
Eotaxin-2 (relative expression level) (median (range))	106 (3.63–433)	12.8 (0.51–65.5)	56.6 (33.2–69.4)	0.134

SPDEF, SAM-pointed dominant-containing Ets-like factor. Analysis of variance.