New Horizons in Research on Diabetic Complications of the Eye: Special Emphasis on Diabetic Cataracts and Retinopathy
1Department of Ophthalmology, Kresge Eye Institute, Wayne State University, 4717 Saint Antoine Street, Room 408, Detroit, MI 48201, USA
2Department of Medicine, Division of Endocrinology, Case Western Reserve University, 10900 Euclid Avenue, BRB 429, Cleveland, OH 44106, USA
3Department of Ophthalmology, Rocky Mountain Lions Eye Institute, Denver Health Science Center, University of Colorado, 12801 E 17th Avenue, MS 8131, Aurora, CO 80045, USA
New Horizons in Research on Diabetic Complications of the Eye: Special Emphasis on Diabetic Cataracts and Retinopathy
Description
The increase in the incidence of diabetes all over the world is expected to translate to a rise in the incidence of its complications, including those affecting the eye such as cataracts and diabetic retinopathy (DR). Although advances in cataract surgery have been successful in restoring vision, such treatment alone has not been able to reduce its high prevalence. Also, the surgical cost is a financial burden in many countries. Development of pharmacological methods for delaying/treating cataracts is hence highly desirable. We invite authors to submit research articles pertaining to studies on the pathogenesis of this disease known to set in earlier and progress faster in diabetics. Papers investigating novel agents with potential for its delay/therapy are also welcomed.
We also invite authors to present original research on DR. The mechanisms leading to a decrease in neural function as well as to the induction of microvascular abnormalities are yet to be elucidated. We welcome authors to submit papers that can contribute to the current literature pertaining to the pathogenesis of DR, identifying targets for therapeutic intervention, as well as investigating novel agents for its treatment.
Potential topics include but are not limited to:
- Molecular and cellular mechanisms, including the role of ROS, in the pathogenesis of cataracts and DR
- Antioxidants and other emerging therapies (e.g. AR and PKC inhibitors, inhibitors of glycation and AGE formation, and modulators of growth factors and cytokines) for DR
- Pharmacotherapy of diabetic cataract
- Animals models of diabetes for studying diabetic cataracts and DR
Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jop/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: