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Multimodal Imaging of the Fundus

Call for Papers

In recent years, new noninvasive modalities for fundus imaging enabled us to obtain high resolution images and functional images of the fundus in patients. These multimodal imaging devices include spectral domain optical coherence tomography (SD-OCT), adaptive optics fundus camera or scanning laser ophthalmoscope, swept source (high penetration) optical coherence tomography (SS-OCT), fundus autofluorescence, laser speckle flowgraphy, and retinal oximetry camera.

With SD-OCT we can evaluate detailed changes in the retina layer by layer, thickness of the choroid, ganglion cell complex, and optic disc. Adaptive optics imaging enables us to observe cone mosaics, retinal capillaries, and nerve fibers. For functional analyses of the retina and the choroid, fundus autofluorescence demonstrates distribution of the lipofuscin in the retinal pigment epithelium and the melanin with short wavelength and near infrared, respectively. Laser speckle flowgraphy expresses in vivo blood flow of the retina, the choroid, and the optic disc as mean blur rate. Retinal oximetry is a newly developed fundus imaging to measure retinal oxygenation.

These new devices reveal various anatomical and functional changes in the fundus by high resolution images, which may develop and improve diagnosis, treatment, and surgical maneuver. We invite authors to submit original research and review articles that aim to describe various issues regarding the multimodal imaging of the fundus in ophthalmology. Potential topics include, but are not limited to:

  • Novel findings of the retina, the choroid, the sclera, and the optic disc with high resolution cross-sectional (or tomographic) images by SD-OCT and/or swept source OCT
  • Morphological and/or functional analysis of the fundus diseases and glaucomatous optic neuropathy by multimodal imaging devices
  • Insights to improve diagnosis, treatment, and surgical maneuver of the fundus diseases with multimodal imaging devices
  • Applications of laser speckle flowgraphy and/or retinal oximetry to study in vivo analyses of ischemic diseases, glaucoma, and other diseases
  • Findings in applications of high resolution imaging devices such as intraoperative use of SD-OCT
  • Comparison of established and novel parameters of ultrahigh resolution images with adaptive optics in the retinal diseases
  • Future machines for high resolution fundus imaging such as SD-OCT or SS-OCT with adaptive optics, Doppler SS-OCT, polarization-sensitive OCT, megahertz SS-OCT for ultrawide field retinal imaging with a 1050 nm mode-locked laser, SD-OCT mounted operating microscope, and devices for morphological and functional analyses of the fundus

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:

Manuscript DueFriday, 18 January 2013
First Round of ReviewsFriday, 12 April 2013
Publication DateFriday, 7 June 2013

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