Journal of Ophthalmology

Application of Optical Coherence Tomography Angiography to Retinal Disease


1University of Illinois at Chicago, Chicago, USA

2Tufts University, Boston, USA

3University of Miami, Coral Gables, USA

4Tufts Medical School, Boston, USA

Application of Optical Coherence Tomography Angiography to Retinal Disease


A little over two years ago, a hot new topic in retinal imaging caught the attention of ophthalmologists around the world. Optical coherence tomography angiography (OCTA), an innovative, fast, noninvasive, non-dye-based angiographic technique, quickly became a topic of great interest in major conferences and ophthalmology journals. Inquisitive minds applied the OCTA prototypes to understanding diseases such as macular degeneration, diabetic retinopathy, and glaucoma. The technology’s high resolution and ability to segment the different vascular layers provided novel insight into disease pathogenesis and morphology. However, as with any new technology, it had limitations such as image artifact and the inability to accurately quantify vascular parameters. Today, advancements in software that address some of the limitations and more widespread access to the OCTA devices allow investigators to further expand upon our collective knowledge of ophthalmologic disease.

The purpose of this special issue is to publish a collection of innovative and high-quality research articles and reviews addressing the application of OCTA to retinal diseases. We invite investigators to submit original research articles and reviews to this special issue.

Potential topics include but are not limited to the following:

  • Reviews of the utility of OCTA in various retinal diseases
  • Changes in vasculature or neovascularization over time
  • Effect of treatment on vascular structures
  • Quantitative assessment or techniques
  • Novel processing or analysis
  • Diabetic retinopathy
  • Age-related macular degeneration
  • Inherited retinal disease
  • Retinal artery occlusion
  • Retinal vein occlusion
  • Ocular tumors


  • Special Issue
  • - Volume 2018
  • - Article ID 5490592
  • - Editorial

Application of Optical Coherence Tomography Angiography to Retinal Disease

Talisa E. de Carlo | Nadia K. Waheed | ... | Daniela Ferrara
  • Special Issue
  • - Volume 2018
  • - Article ID 3751702
  • - Research Article

Optical Coherence Tomography Angiography to Distinguish Changes of Choroidal Neovascularization after Anti-VEGF Therapy: Monthly Loading Dose versus Pro Re Nata Regimen

Alexandra Miere | Hassiba Oubraham | ... | Eric H. Souied
  • Special Issue
  • - Volume 2018
  • - Article ID 2890357
  • - Clinical Study

Changes in Flow Density Measured Using Optical Coherence Tomography Angiography after iStent Insertion in Combination with Phacoemulsification in Patients with Open-Angle Glaucoma

Maged Alnawaiseh | Viktoria Müller | ... | Nicole Eter
  • Special Issue
  • - Volume 2018
  • - Article ID 8125267
  • - Review Article

Choriocapillaris Loss in Advanced Age-Related Macular Degeneration

Carlos A. Moreira-Neto | Eric M. Moult | ... | Daniela Ferrara
  • Special Issue
  • - Volume 2017
  • - Article ID 3479695
  • - Research Article

Sensitivity, Specificity, and Limitations of Optical Coherence Tomography Angiography in Diagnosis of Polypoidal Choroidal Vasculopathy

Yi-Ming Huang | Ming-Hung Hsieh | ... | Shih-Jen Chen
  • Special Issue
  • - Volume 2017
  • - Article ID 6913980
  • - Research Article

Detection of Silent Type I Choroidal Neovascular Membrane in Chronic Central Serous Chorioretinopathy Using En Face Swept-Source Optical Coherence Tomography Angiography

Magdy Moussa | Mahmoud Leila | ... | Mohamed Lolah
Journal of Ophthalmology
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