Journal of Ophthalmology

Retinitis Pigmentosa: Disease Mechanisms, Diagnosis, and Therapies


Status
Published

Lead Editor

1Glasgow Caledonian University, Glasgow, UK

2University of Florida, Gainesville, USA

3Sichuan Academy of Medical Sciences, Chengdu, China

4Inverclyde Royal Hospital, Greenock, UK


Retinitis Pigmentosa: Disease Mechanisms, Diagnosis, and Therapies

Description

Retinitis pigmentosa (RP) is a heterogeneous genetic disorder, characterized by impaired dark adaption and progressive loss of photoreceptor cells. Recent studies using in vitro and in vivo models have accelerated the understanding of disease mechanisms of RP. New technologies (e.g., next generation sequencing) have helped identify novel RP-causing genes and diagnose new RP cases. Advanced imaging diagnostics, successful therapies in animal models, and clinical trials offer hope for RP patients.

We invite investigators to contribute original research papers as well as review articles that will promote the understanding of the pathogenesis, the designing of diagnostic platforms, and the development of new therapeutic strategies. We are particularly interested in articles describing the signalling pathways involved in the disease process, the new high-resolution retinal imaging tools, the molecular diagnostics, and the treatments using small chemicals, natural products, stem cells, and gene therapies.

Potential topics include, but are not limited to:

  • The role of protein trafficking in RP
  • Disease mechanisms from animal models
  • Latest technologies for identifying novel RP-causing genes and diagnosing new RP cases
  • Adaptive optics retinal imaging in RP
  • Gene therapies for RP
  • Embryonic stem cell and induced pluripotent stem cell replacement for RP

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 819452
  • - Editorial

Retinitis Pigmentosa: Disease Mechanisms, Diagnosis, and Therapies

Xinhua Shu | Ji-jing Pang | ... | David Mansfield
  • Special Issue
  • - Volume 2015
  • - Article ID 292615
  • - Research Article

ET-1 Plasma Levels, Aqueous Flare, and Choroidal Thickness in Patients with Retinitis Pigmentosa

Ernesto Strobbe | Mauro Cellini | ... | Emilio C. Campos
  • Special Issue
  • - Volume 2015
  • - Article ID 816329
  • - Research Article

Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish

Yuan Liu | Xue Chen | ... | Chen Zhao
  • Special Issue
  • - Volume 2015
  • - Article ID 250812
  • - Review Article

Histone Deacetylases Inhibitors in the Treatment of Retinal Degenerative Diseases: Overview and Perspectives

Hua Zhang | Xufeng Dai | ... | Ji-jing Pang
  • Special Issue
  • - Volume 2015
  • - Article ID 414781
  • - Review Article

The Role of RPGR and Its Interacting Proteins in Ciliopathies

Sarita Rani Patnaik | Rakesh Kotapati Raghupathy | ... | Xinhua Shu
  • Special Issue
  • - Volume 2015
  • - Article ID 309510
  • - Research Article

Histological Characterization of the Dicer1 Mutant Zebrafish Retina

Saeed Akhtar | Sarita Rani Patnaik | ... | Xinhua Shu
  • Special Issue
  • - Volume 2015
  • - Article ID 145468
  • - Research Article

Eye Motility Alterations in Retinitis Pigmentosa

Raffaele Migliorini | Anna Maria Comberiati | ... | Loredana Arrico
  • Special Issue
  • - Volume 2015
  • - Article ID 942740
  • - Research Article

Exome Sequencing Identified a Recessive RDH12 Mutation in a Family with Severe Early-Onset Retinitis Pigmentosa

Bo Gong | Bo Wei | ... | Houbin Zhang
  • Special Issue
  • - Volume 2015
  • - Article ID 918473
  • - Research Article

iTRAQ-Based Proteomic Analysis of Visual Cycle-Associated Proteins in RPE of rd12 Mice before and after RPE65 Gene Delivery

Qinxiang Zheng | Yueping Ren | ... | Wensheng Li
  • Special Issue
  • - Volume 2015
  • - Article ID 421269
  • - Review Article

Retinitis Pigmentosa Treatment with Western Medicine and Traditional Chinese Medicine Therapies

Jian Xu | Qinghua Peng
Journal of Ophthalmology
 Journal metrics
Acceptance rate36%
Submission to final decision74 days
Acceptance to publication31 days
CiteScore2.800
Impact Factor1.447
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