Review Article

Odanacatib, a New Drug for the Treatment of Osteoporosis: Review of the Results in Postmenopausal Women

Table 1

Effect of 50 mg of odanacatib on formation markers and resorption at 12, 24, and 36 months.

12 months24 months36 months

BSAP−18%−15%+18%
NTx/Cr−60.2%−51.8%−50%
CTx−60%−45%−24%

NTx/Cr: N-terminal telopeptide of type I collagen normalized to creatinine.
BSAP: bone-specific alkaline phosphatase.
CTx: carboxyterminal telopeptide of type I collagen.