Journal of Osteoporosis

Clinical Study

Genetic Influence of Candidate Osteoporosis Genes in Saudi Arabian Population: A Pilot Study

Table 2

(a) Demographic data of LRP5 (C_25752205_10) of CC, CT, and TT alleles. (b) Statistical analysis of the LRP5 (C_25752205_10) 3 alleles.
(a)
ParameterCC (147)CT (46)TT (7)
Age years 6 2 ± 1 0 . 9 6 0 . 4 ± 8 . 9 6 0 ± 1 2
BMD hip g/cm2 0 . 4 4 3 ± 0 . 1 5 0 . 4 4 5 ± 0 . 1 4 0 . 5 3 9 ± 0 . 0 6
T score − 2 . 7 ± 1 . 1 − 2 . 6 5 ± 0 . 8 − 2 . 0 5 ± 0 . 7
Z score − 1 . 5 ± 3 . 6 − 1 . 1 ± 0 . 7 − 0 . 9 ± 0 . 5
BMD spine g/cm2 0 . 6 8 7 ± 1 . 4 0 . 7 0 ± 0 . 1 3 0 . 9 ± 0 . 5
T score − 3 . 1 6 ± 0 . 9 7 − 3 . 2 6 ± 1 . 0 2 − 2 . 3 5 ± 0 . 2 8
Z score − 1 . 8 ± 0 . 9 − 2 . 0 7 ± 1 . 3 − 1 . 7 5 ± 0 . 6
No. of fractures (%)51 (34.2)15 (32.6)0
(b)
ParameterAlleles 𝑃 value (CI)
AgeCC versus CT
CC + CT versus TT		0.7
0.6
BMD hip CC versus CT
CC + CT versus TT		0.8
0.001 (0.065–0.107)
BMD spineCC versus CT
CC + CT versus TT		0.2
0.001 (0.166–2.540)
History of fractures CC versus CT
CC + CT versus TT		0.01 (35.8–36.20)
0.001 (32.8–33.14)