Comparative Evaluation of Enalapril and Losartan in Pharmacological Correction of Experimental Osteoporosis and Fractures of Its Background

Table 2

The average parameters of microcirculation, the width of the bone trabecule in the bony callus and rate of consolidation of the experimental osteoporotic fractures of the proximal part of rats femur, the once received treatment with the studied medication is compared with control group.

Animal group	Level of microcirculation (in PE)	The average width of bone trabeculae (in 𝜇m)	Number of consolidated fractures
The intact with fracture	87.64 ± 6.3	92.93 ± 1.6	16 out of 20
Osteoporosis + fracture	69.7 ± 5.9	59.02 ± 1.7	12 out of 20
Osteoporosis + fracture + enalapril 0.5 mg/kg	102.23 ± 5.4	76.98 ± 1.4	19 out of 20
Osteoporosis fracture + losartan 6 mg/kg	123.11 ± 4.97	81.88 ± 1.8	20 out of 20