Journal of Osteoporosis / 2013 / Article / Fig 2

Review Article

Nanohydroxyapatite Application to Osteoporosis Management

Figure 2

Crystal structure of normal bone (a) and osteoporotic bone (b). Normal crystal structure of the sodium calcium hydrogen carbonate phosphate hydrate with chemical formula Ca8H2(PO4)6 H2O–NaHCO3–H2O. Crystal structure of osteoporotic bone is the calcium phosphate hydroxide with chemical formula Ca10(OH)2(PO4)6. The difference lies in the number of calcium atoms (local hypermineralization) and the presence of H2O–NaHCO3–H2O (substitution/incorporation) [14].

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