Effects of Vitamin E on Bone Biomechanical and Histomorphometric Parameters in Ovariectomized Rats

Table 1

Effects of ovariectomy (Ovx) and three doses of vitamin E: low dose (LD, 300 mg/kg diet), medium dose (MD, 525 mg/kg diet), and high dose (HD, 750 mg/kg diet) on body and tissue weights, serum vitamin E, and serum ALP activity.

Parameters	Sham	Ovx	LD	MD	HD
Body Weight (g)
Initial	299.3±11.8	307.9±8.9	310.4±9.2	307.7±8.9	308.6±8.9
Final	328.0±20.19^a	409.8±11.27^b	406.0±10.37^b	392.9±10.35^b	394.9±8.51^b
Uterine weight (g)	0.710±0.035^a	0.141±0.027^b	0.209±0.031^b	0.144±0.029^b	0.158±0.028^b
Vitamin E (mg/mL)	26.78±2.96^ab	22.47±2.24^b	31.32±2.41^a	29.51±2.24^a	30.98±2.32^a
ALP (U/L)	38.63±2.59^a	46.79±2.89^a	56.54±3.68^a	60.29±5.64^b	61.23±4.46^b

Values within a row that share the same superscript letters are not significantly (𝑃≥.05) different. Values are means ± S.E.M.
ALP: alkaline phosphatase.