Clinical Study

Effect of Simvastatin and Atorvastatin on Serum Vitamin D and Bone Mineral Density in Hypercholesterolemic Patients: A Cross-Sectional Study

Table 4

Results of serum 25-hydroxyvitamin D, lumbar spine BMD, and femoral neck BMD in the study and control groups with regard to supplementation. CI: confidence interval; 25OHD: 25-hydroxyvitamin D; BMD: bone mineral density. Supplementation is in the form of calcium and vitamin D.

ParameterOn supplementationNot on supplementationRegression coefficient (95% CI) value

Serum 25OHDStudy33.41 ± 21.24 ()25.89 ± 14.37 ()7.52 (−1.99–17.02)0.13
Control38.14 ± 20.42 ()28.17 ± 13.98 ()0.06

Lumbar spine BMDStudy1.03 ± 0.131.14 ± 0.15−0.11 (−0.19–−0.04)0.005
Control1.01 ± 0.141.05 ± 0.140.41

Femoral neck BMDStudy0.9 ± 0.130.95 ± 0.17−0.05 (−0.14–0.03)0.19
Control0.86 ± 0.110.88 ± 0.110.62