The Combination Therapy with Zoledronic Acid and Propranolol Improves the Trabecular Microarchitecture and Mechanical Property in an Rat Model of Postmenopausal Osteoporosis

Figure 3

Effects of zoledronic acid and propranolol, alone or in combination, on bone parameters measured by Micro-CT at the distal femur region of ovariectomized rats. Data are shown as the mean ± SD (𝑛=6), evaluated by Tukey’s multiple comparison test. *𝑃<0.05; **𝑃<0.01; ***𝑃<0.001, compared to OVX group;^a𝑃 < 0.05;^b𝑃 < 0.01, compared to ZOL + PRO group. All groups except SHAM group undergo ovariectomy.

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