The Effect of Long-Term Exercise on the Production of Osteoclastogenic and Antiosteoclastogenic Cytokines by Peripheral Blood Mononuclear Cells and on Serum Markers of Bone Metabolism

Figure 2

Effect of exercise on osteoclastogenic cytokine production. Exercise attenuated the production of TNF-α and IFN-γ in both PHA⁻ and PHA⁺ cultures. IL1-α values also fell in PHA⁺ cultures. Preexercise values are represented by the white columns and postexercise values by the black columns. Results are given as the mean ± SEM. indicates a p value of <.05 (two-sided t-test for dependent samples). PHA: phytohemagglutinin.