Table of Contents Author Guidelines Submit a Manuscript
Journal of Osteoporosis
Volume 2016, Article ID 7030272, 10 pages
http://dx.doi.org/10.1155/2016/7030272
Clinical Study

Bone Strength and Arterial Stiffness Impact on Cardiovascular Mortality in a General Population

1JZU Clinical Hospital “Dr. Trifun Panovski”, Department of Internal Medicine, 7000 Bitola, Macedonia
2University Clinic of Obstetrics and Gynecology, Medical Faculty, “Ss. Cyril and Methodius University” in Skopje, 1000 Skopje, Macedonia
3University Clinic of Nephrology, Medical Faculty, “Ss. Cyril and Methodius University” in Skopje, 1000 Skopje, Macedonia

Received 31 October 2015; Revised 6 February 2016; Accepted 14 February 2016

Academic Editor: Merry Jo Oursler

Copyright © 2016 Petar Avramovski et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Y.-Q. Wang, P.-T. Yang, H. Yuan et al., “Low bone mineral density is associated with increased arterial stiffness in participants of a health records based study,” Journal of Thoracic Disease, vol. 7, no. 5, pp. 790–798, 2015. View at Publisher · View at Google Scholar
  2. L. B. Tankó, C. Christiansen, D. A. Cox, M. J. Geiger, M. A. McNabb, and S. R. Cummings, “Relationship between osteoporosis and cardiovascular disease in postmenopausal women,” Journal of Bone and Mineral Research, vol. 20, no. 11, pp. 1912–1920, 2005. View at Publisher · View at Google Scholar
  3. B. Sinnott, I. Syed, A. Sevrukov, and E. Barengolts, “Coronary calcification and osteoporosis in men and postmenopausal women are independent processes associated with aging,” Calcified Tissue International, vol. 78, no. 4, pp. 195–202, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. S. I. McFarlane, G. Qureshi, G. Singh, K. Venner-Jones, L. Salciccioli, and J. Lazar, “Bone mineral density as a predictor of atherosclerosis and arterial wall stiffness in obese African-American women,” Cardiorenal Medicine, vol. 2, no. 4, pp. 328–334, 2012. View at Publisher · View at Google Scholar
  5. H.-Y. Lee and B.-H. Oh, “Aging and arterial stiffness,” Circulation Journal, vol. 74, no. 11, pp. 2257–2262, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. M. Cecelja and P. Chowienczyk, “Role of arterial stiffness in cardiovascular disease,” JRSM Cardiovascular Disease, vol. 1, no. 4, pp. 11–11, 2012. View at Publisher · View at Google Scholar
  7. A. E. Hak, H. A. P. Pols, A. M. van Hemert, A. Hofman, and J. C. M. Witteman, “Progression of aortic calcification is associated with metacarpal bone loss during menopause: a population-based longitudinal study,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 20, no. 8, pp. 1926–1931, 2000. View at Publisher · View at Google Scholar · View at Scopus
  8. M. Sanada, A. Taguchi, Y. Higashi et al., “Forearm endothelial function and bone mineral loss in postmenopausal women,” Atherosclerosis, vol. 176, no. 2, pp. 387–392, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Mikumo, H. Okano, R. Yoshikata, K. Ishitani, and H. Ohta, “Association between lumber bone mineral density and vascular stiffness as assessed by pulse wave velocity in postmenopausal women,” Journal of Bone and Mineral Metabolism, vol. 27, no. 1, pp. 89–94, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. P. Avramovski, P. Janakievska, M. Koneska, K. Sotiroski, and A. Sikole, “Associations between Pulse Wave Velocity, Aortic Vascular Calcification, and Bone Mineral Density in Chronic Hemodialysis Patients and General Population,” ISRN Vascular Medicine, vol. 2013, Article ID 507637, 9 pages, 2013. View at Publisher · View at Google Scholar
  11. O. I. Stojanovic, M. Lazovic, M. Lazovic, and M. Vuceljic, “Association between atherosclerosis and osteoporosis, the role of vitamin D,” Archives of Medical Science, vol. 7, no. 2, pp. 179–188, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. P. Avramovski and A. Sikole, “The progression of bone mineral density loss in dialysis patients compared with the general population,” Korean Journal of Internal Medicine, vol. 27, no. 4, pp. 436–442, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. P. Avramovski, P. Janakievska, K. Sotiroski, and A. Sikole, “Accelerated progression of arterial stiffness in dialysis patients compared with the general population,” Korean Journal of Internal Medicine, vol. 28, no. 4, pp. 464–474, 2013. View at Publisher · View at Google Scholar · View at Scopus
  14. P. Avramovski, M. Avramovska, M. Lazarevski, and A. Sikole, “Femoral neck and spine bone mineral density-Surrogate marker of aortic calcification in postmenopausal women,” The Anatolian Journal of Cardiology, 2015. View at Publisher · View at Google Scholar
  15. C. U. Chae, M. A. Pfeffer, R. J. Glynn, G. F. Mitchell, J. O. Taylor, and C. H. Hennekens, “Increased pulse pressure and risk of heart failure in the elderly,” The Journal of the American Medical Association, vol. 281, no. 7, pp. 634–639, 1999. View at Publisher · View at Google Scholar · View at Scopus
  16. D. M. Kado, W. S. Browner, T. Blackwell, R. Gore, and S. R. Cummings, “Rate of bone loss is associated with mortality in older women: a prospective study,” Journal of Bone and Mineral Research, vol. 15, no. 10, pp. 1974–1980, 2000. View at Publisher · View at Google Scholar · View at Scopus
  17. D. E. R. Warburton, C. W. Nicol, S. N. Gatto, and S. S. D. Bredin, “Cardiovascular disease and osteoporosis: balancing risk management,” Vascular Health and Risk Management, vol. 3, no. 5, pp. 673–689, 2007. View at Google Scholar · View at Scopus
  18. T. M. Doherty, L. A. Fitzpatrick, D. Inoue et al., “Molecular, endocrine, and genetic mechanisms of arterial calcification,” Endocrine Reviews, vol. 25, no. 4, pp. 629–672, 2004. View at Publisher · View at Google Scholar · View at Scopus
  19. Y. Sheu, J. M. Zmuda, R. M. Boudreau et al., “Bone strength measured by peripheral quantitative computed tomography and the risk of nonvertebral fractures: the osteoporotic fractures in men (MrOS) study,” Journal of Bone and Mineral Research, vol. 26, no. 1, pp. 63–71, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. A. El Maghraoui and C. Roux, “DXA scanning in clinical practice,” Quarterly Journal of Medicine, vol. 101, no. 8, pp. 605–617, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. K. Siminoski, W. D. Leslie, H. Frame et al., “Recommendations for bone mineral density reporting in Canada,” Canadian Association of Radiologists Journal, vol. 56, no. 3, pp. 178–188, 2005. View at Google Scholar · View at Scopus
  22. A. Benetos, C. Adamopoulos, J.-M. Bureau et al., “Determinants of accelerated progression of arterial stiffness in normotensive subjects and in treated hypertensive subjects over a 6-year period,” Circulation, vol. 105, no. 10, pp. 1202–1207, 2002. View at Publisher · View at Google Scholar · View at Scopus
  23. J. Calabia, P. Torguet, M. Garcia et al., “Doppler ultrasound in the measurement of pulse wave velocity: agreement with the Complior method,” Cardiovascular Ultrasound, vol. 9, article 13, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. J. A. Kanis, A. Oden, O. Johnell, C. De Laet, B. Jonsson, and A. K. Oglesby, “The components of excess mortality after hip fracture,” Bone, vol. 32, no. 5, pp. 468–473, 2003. View at Publisher · View at Google Scholar · View at Scopus
  25. M. Shiraki, T. Kuroda, and S. Tanaka, “Established osteoporosis associated with high mortality after adjustment for age and co-mobidities in postmenopausal Japanese women,” Internal Medicine, vol. 50, no. 5, pp. 397–404, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. R. A. Adler, Osteoporosis: Pathophysiology and Clinical Management, Humana Press, Totowa, NJ, USA, 2nd edition, 2010.
  27. A. P. Guérin, G. M. London, S. J. Marchais, and F. Metivier, “Arterial stiffening and vascular calcifications in end-stage renal disease,” Nephrology Dialysis Transplantation, vol. 15, no. 7, pp. 1014–1021, 2000. View at Publisher · View at Google Scholar · View at Scopus
  28. P. Raggi, A. Bellasi, E. Ferramosca, G. A. Block, and P. Muntner, “Pulse wave velocity is inversely related to vertebral bone density in hemodialysis patients,” Hypertension, vol. 49, no. 6, pp. 1278–1284, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. R. Bouillon, “Diabetic bone disease,” Calcified Tissue International, vol. 49, no. 3, pp. 155–160, 1991. View at Publisher · View at Google Scholar · View at Scopus
  30. P. Strazzullo, V. Nunziata, M. Cirillo et al., “Abnormalities of calcium metabolism in essential hypertension,” Clinical Science, vol. 65, no. 2, pp. 137–141, 1983. View at Publisher · View at Google Scholar · View at Scopus
  31. J. L. Pérez-Castrillón, I. Justo, J. Silva et al., “Bone mass and bone modelling markers in hypertensive postmenopausal women,” Journal of Human Hypertension, vol. 17, no. 2, pp. 107–110, 2003. View at Publisher · View at Google Scholar · View at Scopus
  32. S. Yazici, M. Yazici, U. Korkmaz et al., “Relationship between blood pressure levels and bone mineral density in postmenopausal Turkish women,” Archives of Medical Science, vol. 7, no. 2, pp. 264–270, 2011. View at Publisher · View at Google Scholar · View at Scopus
  33. N. L. Kim, H. M. Jang, S. K. Kim, K. D. Ko, I. C. Hwang, and H. S. Suh, “Association of arterial stiffness and osteoporosis in healthy men undergoing screening medical examination,” Journal of Bone Metabolism, vol. 21, no. 2, pp. 133–141, 2014. View at Publisher · View at Google Scholar
  34. L. L. Demer, “Vascular calcification and osteoporosis: inflammatory responses to oxidized lipids,” International Journal of Epidemiology, vol. 31, no. 4, pp. 737–741, 2002. View at Publisher · View at Google Scholar · View at Scopus
  35. Y. Shimizu, M. Nakazato, T. Sekita et al., “Association of arterial stiffness and diabetes with triglycerides-to-HDL cholesterol ratio for japanese men: the nagasaki islands study,” Atherosclerosis, vol. 228, no. 2, pp. 491–495, 2013. View at Publisher · View at Google Scholar · View at Scopus
  36. C. Vlachopoulos, K. Aznaouridis, and C. Stefanadis, “Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis,” The Journal of the American College of Cardiology, vol. 55, no. 13, pp. 1318–1327, 2010. View at Publisher · View at Google Scholar · View at Scopus
  37. J. Blacher, R. Asmar, S. Djane, G. M. London, and M. E. Safar, “Aortic pulse wave velocity as a marker of cardiovascular risk in hypertensive patients,” Hypertension, vol. 33, no. 5, pp. 1111–1117, 1999. View at Publisher · View at Google Scholar · View at Scopus
  38. T. Shoji, M. Emoto, K. Shinohara et al., “Diabetes mellitus, aortic stiffness, and cardiovascular mortality in end-stage renal disease,” Journal of the American Society of Nephrology, vol. 12, no. 10, pp. 2117–2124, 2001. View at Google Scholar · View at Scopus
  39. K. Sutton-Tyrrell, S. S. Najjar, R. M. Boudreau et al., “Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults,” Circulation, vol. 111, no. 25, pp. 3384–3390, 2005. View at Publisher · View at Google Scholar · View at Scopus
  40. P. Avramovski, P. Janakievska, K. Sotiroski, B. Zafirova-Ivanovska, and A. Sikole, “Aortic pulse wave velocity is a strong predictor of all-cause and cardiovascular mortality in chronic dialysis patients,” Renal Failure, vol. 36, no. 2, pp. 176–186, 2014. View at Publisher · View at Google Scholar · View at Scopus
  41. G. N. Farhat and J. A. Cauley, “The link between osteoporosis and cardiovascular disease,” Clinical Cases in Mineral and Bone Metabolism, vol. 5, no. 1, pp. 19–34, 2008. View at Google Scholar · View at Scopus
  42. R. Vattikuti and D. A. Towler, “Osteogenic regulation of vascular calcification: an early perspective,” The American Journal of Physiology—Endocrinology and Metabolism, vol. 286, no. 5, pp. E686–E696, 2004. View at Publisher · View at Google Scholar · View at Scopus
  43. S. I. McFarlane, R. Muniyappa, J. J. Shin, G. Bahtiyar, and J. R. Sowers, “Osteoporosis and cardiovascular disease: brittle bones and boned arteries, is there a link?” Endocrine, vol. 23, no. 1, pp. 1–10, 2004. View at Publisher · View at Google Scholar · View at Scopus