Research Article

The Effects of Noncompliance to Prolia (Denosumab) on the Changes in Bone Mineral Density: A Retrospective Review

Table 2

Participant characteristics stratified by time of denosumab injection after one-year follow-up.

CharacteristicTime of subsequent injection of denosumab
<5 months5–7 months>7 months

BMD, mean (SD)
 Lumbar spine0.909 (0.141)0.840 (0.137)0.849 (0.102)
 Femoral neck0.655 (0.080)0.638 (0.104)0.635 (0.097)
 Incident nonvertebral fracture, % ()0.0% (0)2.47% (9)3.39% (2)
 Incident vertebral fracture, % ()0.0% (0)0.0% (0)0.0% (0)

Mean duration of treatment from baseline injection in months (SD)3.03 (1.18)6.05 (0.38)9.43 (3.05)