Monitoring of Cellular Changes in the Bone Marrow following PTH(1-34) Treatment of OVX Rats Using a Portable Stray-Field NMR Scanner

Table 1

Animals and bones average weights in the prevention experiment (6 weeks after operation) and in the therapeutic treatment experiment (11 weeks after operation).

Experiment	Group	Animals weights (gr)	femurs	Femurs weight (gr)	tibiae	Tibiae weight (gr)
Prevention	SHAM		8		8
	OVX		8		8
	OVX + PTH		8		8
Therapeutic treatment	SHAM		10		10
	OVX		10		10
	OVX + PTH		12		12

Sham: Sham operated control rats treated with saline; OVX: ovariectomized rats treated with saline; OVX + PTH: PTH-treated ovariectomized rats. In the prevention experiment, a significant increase in the mean weight of OVX rats was found after 6 weeks, compared to the Sham control mean weight (). No significant changes in the animal’s weights were measured at 6 weeks between OVX and OVX + PTH groups. Increase of the OVX + PTH tibiae average weight compared to Sham group () and compared to OVX group () was found. No significant changes were measured of the average weight of the femurs bones. In the therapeutic treatment experiment, a significant increase in the OVX mean animal weights compared to the Sham control mean weight () was observed 11 weeks after operation. No significant changes in the animal’s weights were measured between OVX and OVX + PTH groups. In this experiment, only femurs mean weight significantly increased in the OVX + PTH compared to OVX femurs mean weight (). No significant changes were measured in the tibiae bones average weight between the three groups.