Journal of Osteoporosis

New Issues in the Management of Osteoporosis

Publishing date
15 Jun 2011
Submission deadline
15 Dec 2010

Lead Editor

1Bone and Cartilage Research Unit, University of Kuopio, 70211 Kuopio, Finland

2Department of Internal Medicine/Metabolic Bone Diseases, Autonomous University of Madrid, 28050 Madrid, Spain; Fundacion Jimenez Diaz, Spain

3Institute for Integrated Sports Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan

New Issues in the Management of Osteoporosis


Osteoporosis results in significant morbidity and medical costs while effective treatment options are also evolving.

Bisphosphonates (BPs) are considered standard antiosteoporotic medication. Other antiresorptive treatment options of osteoporosis include selective oestrogen receptor modulators, hormone therapy, tibolone, and calcitonin. In addition, bone anabolic strontium ranelate is available for primary treatment of osteoporosis, and parathyroid hormone for more severe bone fragility. RANK/RANKL induced osteoclast activity modulating denosumab is the newest compound for the treatment of osteoporosis. These osteoporosis medications are, in most cases, combined into relevant doses of calcium and vitamin D.

Although the efficacy of BPs in controlled trials is evident, there are concerns with regards to adherence and compliance. This precludes the antifracture efficacy of some bisphosphonate regimens, especially oral substances, in clinical setting. In addition, it has been speculated that long-term use of BPs could result in pathologic fractures.

The long-term bone protective and possible adverse effects of the other osteoporosis medications also need further research. Furthermore, there have been reports on extraskeletal effects of vitamin D on falls, strontium ranelate on osteoarthritis, and denosumab on bone erosions in rheumatoid arthritis which need more detailed appraisal. Also, the effects of different osteoporosis medications on fracture healing remain to be unresolved.

The main focus of this special issue is on new issues in the management of osteoporosis. We seek both original experimental or clinical research papers as well as review articles. The special issue will become a critical forum for researchers to discuss the most relevant issues on treatment of osteoporosis. The topics to be covered include, but are not limited to:

  • Incidence and mechanisms of pathologic fractures and other adverse effects due to BPs
  • New methods for improving targeting of and adherence to the treatment of osteoporosis
  • Long-term efficacy of BPs and other osteoporosis therapies
  • Factors behind nonresponse to BPs and other osteoporosis therapies
  • The effects of osteoporosis risk assessment tools on cost effectiveness of osteoporosis treatment
  • Extraskeletal effects of osteoporosis therapies
  • Future and experimental therapies for osteoporosis
  • Effects of osteoporosis medication on fracture healing
  • New preventive strategies for management of osteoporosis

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:


  • Special Issue
  • - Volume 2011
  • - Article ID 582789
  • - Editorial

New Issues in the Management of Osteoporosis

Joonas Sirola | Manuel Diaz Curiel | ... | Jun Iwamoto
  • Special Issue
  • - Volume 2011
  • - Article ID 536735
  • - Review Article

Similarities in Acquired Factors Related to Postmenopausal Osteoporosis and Sarcopenia

Joonas Sirola | Heikki Kröger
  • Special Issue
  • - Volume 2011
  • - Article ID 732560
  • - Research Article

Mikkeli Osteoporosis Index Identifies Fracture Risk Factors and Osteoporosis and Intervention Thresholds Parallel with FRAX

Ville Juhana Waris | Joonas P. Sirola | ... | V. Pekka Waris
  • Special Issue
  • - Volume 2011
  • - Article ID 363617
  • - Research Article

The Effects of Parathyroid Hormone Applied at Different Regimes on the Trochanteric Region of the Femur in Ovariectomized Rat Model of Osteoporosis

M. Tezval | A. Banhardt | ... | E. K. Stuermer
  • Special Issue
  • - Volume 2011
  • - Article ID 754972
  • - Review Article

Bisphosphonates and Atypical Fractures of Femur

Tero Yli-Kyyny
  • Special Issue
  • - Volume 2011
  • - Article ID 147689
  • - Review Article

The Facial Skeleton in Patients with Osteoporosis: A Field for Disease Signs and Treatment Complications

Athanassios Kyrgidis | Thrasivoulos-George Tzellos | ... | Konstantinos Antoniades
Journal of Osteoporosis
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