Effects of Pregnancy and Bacterial Vaginosis on Proinflammatory Cytokine and Secretory Leukocyte Protease Inhibitor Concentrations in Vaginal Secretions

Table 1

Linear regression models* for the effect of pregnancy and bacterial vaginosis on log-transformed vaginal cytokine and SLPI concentrations.

	Coefficient	95% Confidence Interval	$P$-value
Interleukin-1$\beta$
Pregnancy	0.199	($-$0.019 to 0.416)	.07
BV	0.763	(0.542 to 0.984)	$<$.001
Interleukin-6
Pregnancy	0.025	($-$0.139 to 0.189)	.76
BV	0.125	($-$0.041 to 0.291)	.14
Interleukin-8
Pregnancy	0.255	(0.048 to 0.462)	.02
BV	0.216	(0.006 to 0.426)	.04
SLPI**
Pregnancy	0.408	(0.280 to 0.537)	$<$.001
BV	$-$0.397	($-$0.529 to $-$0.266)	$<$.001

*Models contain the analyte of interest as the dependent variable and covariates for BV, pregnancy, race (as an indicator variable), and age (as a continuous variable). **Restricted to women who were acid phosphatase negative.