Research Article
[Retracted] Antenatal Steroid Therapy for Fetal Lung Maturation and the Subsequent Risk of Childhood Asthma: A Longitudinal Analysis
Table 3
Association between antenatal steroid therapy exposure and childhood asthma.
| | Adjusted | Unadjusted | | HR | 95% CI | HR | 95% CI |
| Antenatal steroid exposure | | | | | 3–5 years | 1.19 | 1.03–1.39 | 1.55 | 1.36–1.77 | 6–7 years | 1.06 | 0.86–1.30 | 1.36 | 1.12–1.65 | 8+ years | 0.74 | 0.54–1.03 | 0.98 | 0.72–1.34 |
| Male gender | 1.24 | 1.21–1.28 | — | | Preterm birth (<37 weeks) | 1.03 | 0.95–1.12 | — | |
| Number of siblings | | | | | 0 | 1.00 | — | | | 1 | 0.90 | 0.88–0.93 | — | | 2 | 0.78 | 0.74–0.82 | — | | 3+ | 0.67 | 0.62–0.72 | — | |
| Bronchopulmonary Dysplasia | 0.98 | 0.74–1.31 | — | | Hyaline Membrane Disease | 1.14 | 1.01–1.30 | — | | Surfactant Administration | 1.07 | 0.82–1.40 | — | |
| 1 Minute Apgar Score | | | | | 0–3 | 1.00 | — | | | 4–6 | 0.95 | 0.86–1.05 | — | | 7–10 | 0.87 | 0.79–0.95 | — | |
| Caesarean section | 1.11 | 1.07–1.15 | — | | Maternal smoking | 1.12 | 1.09–1.16 | — | | Birth weight (per 500 grams) | 1.00 | 0.98–1.01 | — | | Gestational age (weeks) | 0.97 | 0.96–0.98 | — | |
| Birth year | | | | | 1989 | 1.47 | 1.37–1.59 | | | 1990 | 1.45 | 1.35–1.56 | — | | 1991 | 1.49 | 1.39–1.60 | — | | 1992 | 1.28 | 1.19–1.37 | — | | 1993 | 1.21 | 1.12–1.30 | — | | 1994 | 1.14 | 1.06–1.23 | — | | 1995 | 1.12 | 1.04–1.20 | — | | 1996 | 0.99 | 0.92–1.07 | — | | 1997 | 1.02 | 0.95–1.11 | — | | 1998 | 1.00 | — | | |
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Note: Adjustment for all other confounders in table.
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