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Journal of Pregnancy
Volume 2011, Article ID 286483, 4 pages
Research Article

The Influence of Prior Obstetrical History on Current 17-Hydroxyprogesterone Caproate Use

1Department of Obstetrics and Gynecology, Duke University Medical Center (DUMC), P.O. Box 3967, Durham, NC 27710, USA
2Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT. 84132, USA

Received 1 March 2011; Accepted 12 May 2011

Academic Editor: Jerome Cornette

Copyright © 2011 Carla E. Ransom et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To determine if gestational age of prior preterm delivery influences a woman's receipt of 17-hydroxyprogesterone caproate (17-OHP-C). Methods. Retrospective cohort of women eligible for 17-OHP-C at Duke Obstetrics Clinic were identified by medical record review. Sociodemographic and clinical characteristics were abstracted. Results. Of 104 eligible subjects, 82 (78.8%) were offered 17-OHP-C. Of these, thirty-four (41.5%) declined. The median gestational age of the most recent preterm delivery was significantly lower among subjects who accepted 17-OHP-C as compared to those who declined (28.7 vs. 34.0 weeks, ) and in subjects offered 17-OHP-C compared to those not offered 17-OHP-C (30.2 vs. 36.0 weeks, ). Subjects not offered 17-OHP-C were more likely to have had an interval term delivery (31.8% vs. 9.7%, ) Conclusion. Women with earlier preterm deliveries were more likely to be offered and accept 17-OHP-C. Prior obstetric history may influence both providers' and patients' willingness to discuss and/or accept 17-OHP-C.