Clinical Study
Recurrence of Congenital Heart Disease in Cases with Familial Risk
Screened Prenatally by Echocardiography
Table 3
Relative risks ratios—comparison between our series and normal population (Moons et al.).
| | CHD | Our series (‰) | Moons et al. (‰) | RR | Confidence limits (95%) | P-value |
| | HLV | 1/1634 (.6 ) | 10/111225 (.09) | 6.8 | 0.9–53.2 | 0.067 | | UHV | 1/1634 (.6) | 9/111225 (.08) | 7.6 | 0.96–59.8 | 0.055 | | TF | 9/1634 (5.5) | 52/111225 (.5) | 11.8 | 5.8–24.1 | 0.0001 | | PA + VSD | 1/1634 (.6) | 6/111225 (.05) | 11.4 | 1.4–94.3 | 0.024 | | PAIVS | 2/1634 (1.2) | 6/111225 (.05) | 29.7 | 4.6–112.6 | 0.0001 | | Truncus | 1/1634 (.6) | 7/111225 (.06) | 13.7 | 1.7–111.1 | 0.0145 | | TGA | 3/1634 (1.8) | 29/111225 (.3) | 7.05 | 2.1–23.2 | 0.0013 | | TGAc | 1/1634 (.6 ) | 3/111225 (.03) | 22.7 | 24–218 | 0.007 | | CoA | 3/1634 (1.8) | 46/111225 (.4) | 4.5 | 1.4–14.3 | 0.0123 | | AVSD | 5/1634 (3.1) | 37/111225 (.3) | 9.2 | 3.6–23.5 | 0.38 | | Ebstein | 2/1634 (1.2) | 3/111225 (.03) | 63.8 | 10.7–382.4 | <0.0001 | | PS | 3/1634 (1.8) | 88/111225 (.8) | 2.3 | 0.7–7.3 | 0.007 | | As | 5/1634 (3.1) | 26/111225 (.2) | 18.5 | 7.1–48.1 | <0.0001 | | ASD | 8/1634 (4.9) | 162/111225 (1.5) | 4.7 | 2.3–9.7 | <0.0001 | | VSD | 10/1634 (6.1) | 303/111225 (2.7) | 2.3 | 1.9–4.2 | 0.0008 | | T/PAPVD | 1/1634 (.6) | 28/111225 (.3) | 3.4 | 0.46–25.1 | 0.2277 |
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CHD: congenital heart disease, HLV: hypoplastic left ventricle, UVH: univentricular heart, TF: Tetralogy of Fallot, PAtr: pulmonary atresia, PAIVS: pulmonary atresia + intact ventricular septum, TGA: transposition of great arteries, TGAc: corrected transposition of great arteries, CoA: coarctation of aorta, AVSD: atrioventricular septal defect, PS: pulmonary stenosis, AS: aortic stenosis, ASD: atrial septal defect ostium secundum, VSD: ventricular septal defect, T/PAPVD: total/partial anomalous pulmonary venous drainage.
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