Differential Gene Expression Analysis of Placentas with Increased Vascular Resistance and Pre-Eclampsia Using Whole-Genome Microarrays
Figure 2
Protein expression validation with antibody microarray. Protein expression profiling of PE (grey bars) versus N (open bars) using recombinant antibody microarray analysis. A focused microarray composed of 11 scFv antibodies directed against 4 proteins, including TGF-β1, VEGF, C5, and RANTES was applied. Six PE samples and five control samples were analysed. The index (1), and so forth, indicate the clone number of the antibody used, meaning that several clones targeting different epitopes on the same analyte was used to further strengthen the data. The expression levels between PE and N were found to be significant () for all four analytes.
