Research Article

Effect of Angiotensin II on the Left Ventricular Function in a Near-Term Fetal Sheep with Metabolic Acidemia

Table 2

Invasively monitored fetal hemodynamic parameters and acid-base status at baseline and during angiotensin II infusion. Data are presented as mean (SD).

ParameterBaselineAngiotensin II value

Heart rate, beats/min153 (41)170 (40)0.337
Systolic BP, mmHg55 (8)83 (18)<0.001
Diastolic BP, mmHg38 (5)56 (12)<0.001
Mean arterial pressure, mmHg43 (6)65 (14)<0.001
Central venous pressure, mmHg9 (2)14 (13)0.327
pH7.11 (0.12)7.04 (0.16)0.003
Base excess, mmol/Lāˆ’9.4 (5.0)āˆ’11.7 (6.96)0.029
PCO2, kPa8.6 (2.3)9.3 (2.3)0.020
PO2, kPa2.4 (0.9)1.5 (0.8)0.004
Lactate, mmol/L7.6 (3.7)7.4 (2.8)0.701