Journal of Pregnancy / 2012 / Article / Tab 3

Research Article

Migraine-Asthma Comorbidity and Risk of Hypertensive Disorders of Pregnancy

Table 3

Unadjusted and adjusted odds ratios (ORs) and 95% confidence intervals (CIs) of hypertensive disorders of pregnancy in relation to maternal migraine and asthma status, Seattle and Tacoma, WA, USA, 1996–2008.

OutcomesNo migraine/no asthmaMigraine onlyAsthma onlyComorbid Migraine-Asthma

Pregnancy-induced hypertension (PIH)
 No, 𝑛 240447932682
 Yes, 𝑛 167562717
Unadjusted OR (95% CI)1.00 (reference)1.68 (1.22–2.31)1.19 (0.78–1.82)2.98 (1.73–5.15)
1Adjusted OR (95% CI)1.00 (reference)1.20 (0.84–1.71)1.04 (0.66–1.63)2.53 (1.39–4.61)
2Adjusted OR (95% CI)1.00 (reference)1.21 (0.85–1.74)1.03 (0.66–1.62)2.55 (1.40–4.63)

Preeclampsia (PE)
 No, 𝑛 240447932682
 Yes, 𝑛 7219208
Unadjusted OR (95% CI)1.00 (reference)1.32 (0.79–2.22)2.05 (1.23–3.41)3.26 (1.52–6.99)
1Adjusted OR (95% CI)1.00 (reference)0.83 (0.46–1.50)1.89 (1.08–3.28)3.53 (1.51–8.24)
2Adjusted OR (95% CI)1.00 (reference)0.89 (0.49–1.63)2.00 (1.14–3.49)3.77 (1.61–8.82)

PIH or PE
 No, 𝑛 240447932682
 Yes, 𝑛 239754725
Unadjusted OR (95% CI)1.00 (reference)1.58 (1.19–2.08)1.45 (1.04–2.02)3.07 (1.92–4.89)
1Adjusted OR (95% CI)1.00 (reference)1.13 (0.82–1.55)1.27 (0.88–1.83)2.64 (1.56–4.47)
2Adjusted OR (95% CI)1.00 (reference)1.15 (0.84–1.59)1.28 (0.88–1.84)2.69 (1.59–4.56)

Note: Subjects with unknown hypertensive disorder status were excluded from this analysis.
1Adjusted for maternal age, race/ethnicity, parity, marital status, cigarette smoking status, history of chronic hypertension, and pre-pregnancy body mass index.
2Adjusted for maternal age, race/ethnicity, parity, marital status, cigarette smoking status, history of chronic hypertension, pre-pregnancy body mass index, and multifetal pregnancy.