Revisiting the Role of First Trimester Homocysteine as an Index of Maternal and Fetal Outcome

Table 1

Homocysteine levels with reference to outcome of past pregnancies.

	No past history of hypertensive disorder of pregnancy; (𝑛 = 86)	Past history of hypertensive disorder of pregnancy; (𝑛 = 14)	𝑃 value	Statistical test used
Serum homocysteine (𝜇mol/L)	13.11 ± 5.81	19.13 ± 9.34	0.04 *	Unpaired 𝑡-test—Welch correction
	No prior gdm; (𝑛 = 95)	Prior gdm; (𝑛 = 5)
Serum homocysteine (𝜇mol/L)	13.83 ± 6.82	20.39 ± 7.05	0.054	Unpaired 𝑡-test
	No prior preterm delivery; (𝑛 = 94)	Prior preterm delivery; (𝑛 = 6)
Serum homocysteine (𝜇mol/L)	14.33 ± 7.20	13.76 ± 4.20	0.83	Mann-Whitney 𝑈 test
	No previous fetal malformation; (𝑛 = 98)	Previous fetal malformation; (𝑛 = 2)
Serum homocysteine (𝜇mol/L)	14.01 ± 6.80	23.88 ± 9.12	0.08	Mann-Whitney 𝑈 test

^∗𝑃≤0.05 significant.