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Journal of Pregnancy
Volume 2014, Article ID 193925, 5 pages
http://dx.doi.org/10.1155/2014/193925
Research Article

A Prospective Study of Villous Capillary Lesions in Complicated Pregnancies

1Department of Pathology, Sree Balaji Medical College and Hospital, Bharath University, Chennai, Tamil Nadu 600 044, India
2Department of Obstetrics and Gynaecology, Sree Balaji Medical College and Hospital, Bharath University, Chennai, Tamil Nadu 600 044, India

Received 31 July 2014; Revised 11 November 2014; Accepted 12 November 2014; Published 24 November 2014

Academic Editor: Sinuhe Hahn

Copyright © 2014 Anu Priyadharshini Srinivasan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The vascularity of placental tissue is dependent on various factors of which fetomaternal hypoxia plays a major role. Hypoxia can be of different types and each type influences the vascularity of the villi, especially terminal villi, in its own way. In this study, we attempted to identify villous vascular changes in a group of term placentae from mothers with diseases complicating pregnancy. Chorangiosis was the most frequently identified lesion while chorangioma was found in only 2 cases. There were no cases of chorangiomatosis. A few cases had normal villous vasculature. Maternal diseases have a major role in disrupting the placental vasculogenesis and angiogenesis by creating a hypoxic environment that may affect the fetus adversely. Hence, such conditions need to be identified early in pregnancy and managed appropriately as it is possible to maintain a normal vasculature and prevent neonatal mortality and morbidity if prompt intervention is done.